Introducing Our Cutting-Edge Medical Device: I2F

We are thrilled to present our groundbreaking medical device designed specifically for healthcare professionals like you. At AII, we understand that your expertise and dedication are at the heart of exceptional patient care. That’s why we have developed this device, a true game-changer in the infusion industry. The inventor of this device has been a nurse for nearly 30 years.

The problem was observed while working with immunosuppressed patients receiving IVIG infusions. The process of pooling the medications into a pooling bag caused the medication to foam in the glass bottle. After the pooling of the bottle, the bottle was thrown away along with all of the foaming medication. The thoughtful nurse stored many bottles and assessed them after hours of sitting on a shelf. The medication condensed back down to liquid form. After observing this for a few years and measuring hundreds of bottles after sitting on a shelf, it was calculated that the foaming caused between from 2 to 5 % of waste.

Many studies and reports have been analyzed including those on the pharmacokinetics of Intravenous Immunoglobulin and timing of infections in patients with primary immunodeficiencies which encouraged the development of I2F.

Research has found that a greater number of infections were noted in the time period greater than 18 days after infusion, with higher rates of health care utilization over a period of seven months. It’s known that serum IgG levels increased by approximately 2.5 g/L for every 0.1 g/kg of IGIV infused. It’s also known that patients on average are most susceptible to opportunistic infections during their trough period. If we can increase the IgG levels by 2-5%, that could mean the difference between getting an infection or not. Hospitalization costs are significant to payers so the goal is to decrease the risk for hospitalizations with that extra 2-5% that is currently wasted.
I2F is user-friendly and ensures that your patients will receive their full dose of medication, providing many health benefits.

When plasma-derived medications that are in glass bottles are infused or pooled by the current method (vented spike set), it causes the medication to foam. This foaming amounts to 2 to 5% of waste.

In our testing, using the I2F to pool medications in to an infusion bag actually saved nursing/pharmacist time too.

Adopting the use the I2F will seamlessly integrates into your workflow. I2F is inserted next to the IV spike set.

Our device has been rigorously tested to meet the highest industry standards and adheres to strict quality control measures.
I2F is proudly made in the USA.

List of medications that I2F can be used with.

• Albumin

• Alpha 1-Proteinase Inhibitor

• Anti-Inhibitor Coagulation Complex (AICC)

• Anti-Thrombin III Concentrate

• Asceniv

• Bivigam

• Carimune

• CytoGam

• Cytomegalovirus (CMV)

• Factor IX Concentrate

• Factor VIII Concentrate

• Flebogamma

• Gammagard

• Gammaked

• Gammaplex

• Gamunex C

• Immune Globulins, including Rh Immune Globulin

• Octagam

• Panzyga

• Privigen